Erectile
dysfunction is often thought of as an issue that primarily affects older men.
Yet,
nearly 20 per cent of men under the age of 40 are affected by the disorder,
researchers said.
It
was already known that erectile dysfunction is linked to cardiovascular disease
risk factors – including hyperlipidemia, hypertension, obesity, diabetes and
smoking.
The
disorder has also already been recognized as a risk factor for stroke and
coronary heart disease – in addition to angina myocardial infarction.
The
link between erectile dysfunction and cardiovascular risk may arise as a result
of endothelial cell dysfunction and impaired production of nitrous oxide, the
scientists said.
To
arrive at their conclusions, they examined data from 1,790 men between the ages
of 20 to 85 who participated in the 2003-2004 National Health and Nutrition
Examination Survey.
They
linked the survey data with death certificates from the National Death Index
through December 21, 2011.
These
findings have major public health and clinical implications in that erectile
dysfunction is a strong predictor of premature mortality
Erectile
dysfunction was measured by asking: ‘How would you describe your ability to get
and keep an erection adequate for satisfactory intercourse?’
Those
who answered ‘sometimes able’ or ‘never able’ were determined to have the
disorder.
The
scientists found that 557 of the survey participants had erectile dysfunction.
After
a follow-up of nearly eight years, 244 of the original group had died.
Of
those deaths, 61 were from cardiovascular disease, 64 from malignant neoplasms,
12 from chronic lower respiratory diseases and the remainder form a myriad of
causes.
The
scientists adjusted the results to take into account age, physical activity,
race-ethnicity, waist circumference, poverty-to-income ratio, cotinine and
comorbid illness.
They
then concluded that the survey participants who suffered erectile dysfunction
had a 70 per cent increased risk of premature overall mortality.
The
study said: ‘This finding should, however, be interpreted with caution as among
the evaluated sample of 1,790 adults, only 61 adults between 20 to 49 years had
erectile dysfunction, and among these 61 patients, only four died during the
follow-up period.’
The
scientists said the results were also potentially limited by the self-report
assessment of erectile dysfunction.
However,
they also stated that the major strengths of the study include its novelty and
utilization of a national sample.
Further
research is needed to see the long-term results over a longer follow-up period,
the researchers concluded.
The
study said: ‘These findings have major public health and clinical implications
in that erectile dysfunction is a strong predictor of premature mortality.’
The
study was published in the Journal of Sexual Medicine.
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