Against the widespread criticism that Nigerian research institutes are not working towards the development of local drugs to combat the dreaded Ebola Virus Disease (EVD), the Director General, National Institute of Pharmaceutical Research and Development (NIPRD) Professor Karniyus Gamaniel has identified fifteen likely herbs, which when developed could possibly cure Ebola.
According to
him :"As at today, up to 15 of such medicinal plants have been so
identified and work is on-going to ascertain their immunogenic and antiviral
activities. Efforts are now being stepped up on to provide the specific
facilities required for screening and working with the deadly Ebola virus in
the institute and to identify competent collaborators on this assignment.
Meanwhile, an internal call for research proposals was made in the Institute on
Friday 15th of August for Research Fellows to come up with innovative research
plans including those responding to this urgent National Health Emergency on
EV."
The
NIPRD DG, who spoke with topsyoba in an exclusive online chat,noted that
the institute has signed a partnership agreement with the Lagos University
Teaching Hospital (LUTH) in order to work with renown virologist like Prof.
Omilabu who
has sufficient
experience to handle Victims of the EVD.
Asked
whether the specie of Tobacco found in ZMapp is available in Nigeria, he said :
"Tobacco is Nicotiana tabacum and
it is found in Nigeria. But the strain used for the cultivation of the
antibodies used for ZMapp might not be found here. We should know that tobacco
plant is not part of the recipe for ZMapp, the plant was only
used as carrier to multiply the artificial antibodies which was later extracted
from the plant to make the recipe for the treatment. The artificial
antibodies used in the ZMappTM treatment were created from a particular tobacco-plant
strain found in Australia. The plants were genetically modified to serve
as an ideal medium to grow the massive amounts of the antibodies needed for the
treatment. The antibodies were then harvested and ground into the green mix
used in the serum doses. Charles Arntzen, a plant biotechnology expert at
Arizona State University, says that the appropriate viral genes for the
antibodies that the scientists want are fused to the tobacco genes,
infecting the tobacco with the virus. The plant produces antibodies that are
subsequently separated from the plant when it is ground up."
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